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Immunology Services |
Goal of Offering: a complementary menu of complex functional immunoassays to support preclinical research and clinical trials with testing capabilities for both non-infectious and infectious samples in a BSL-2+ laboratory environment. All offerings are customizable to client needs and methodology.
ELISA
- Lymphokines
- Chemokines
- Quantitative assays for protein
- Current qualified offerings: HIV-1 P24, HIV-1 LAg-avidity
- Rapid expansion potential to wide array of human, rodent, NHP, and pig protein targets and pathogens using off-the-shelf kits; single- and multi-plex
ELISpot/Fluorospot
- Lymphokines
- Antibody secretion
- Current qualified offerings: IFNg
- Disease-specific illustrative data for HIV-1
- T Cell Targets: off-the-shelf kits for wide array of human, mouse, rat, pig, and NHP targets
- B Cell Targets: off-the-shelf kits for detection and quantification of antibody secreting cells: human, mouse, ferret, and pig.
Immunogenicity Testing
- Anti-drug antibodies
- Neutralizing antibodies (NAb); cell-based and ligand binding
Flow Cytometry Services (two CytoFLEX instruments, up to 9 colors)
Phenotyping:- Custom panel development and basic qualification in estimated 2 weeks
- Confirmed human cell phenotyping panels: T Cell, B Cell, Granulocyte, and ICS (IL2, IFNg, Granzyme B, Perforin)
- Mechanism of Action
- Proliferation
- Cytotoxicity
Learn More About Phenotyping Learn More About Functional Cell-Based Assays